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Vetenskapliga studier

FUNKTIONSMEDICIN

Teori & bakgrund

Bland JS. Systems Biology Meets Functional Medicine. Integr Med (Encinitas). 2019 Oct;18(5):14-18.

Bland JS, Minich D. Personalized lifestyle medicine: relevance for nutrition and lifestyle recommendations. ScientificWorldJournal. 2013 Jun 26;2013:129841.

Buford TW. Toward exercise as personalized medicine. Sports Med.
2013 Mar;43(3):157-65.

Choi SW, Friso S. Epigenetics: A New Bridge between Nutrition and Health. Adv Nutr. 2010 Nov;1(1):8-16.

DeBusk R, Sierpina VS, Kreitzer MJ. Applying functional nutrition for chronic disease prevention and management: bridging nutrition and functional medicine in 21st century healthcare. Explore (NY). 2011 Jan-Feb;7(1):55-7.

Ford D, Raj S, Batheja RK et al. American Dietetic Association: standards of practice and standards of professional performance for registered dietitians (competent, proficient, and expert) in integrative and functional medicine. J Am Diet Assoc. 2011 Jun;111(6):902-913.e1-23.

Guarneri M, Mercado N, Suhar C. Integrative approaches for cardiovascular disease. Nutr Clin Pract. 2009 Dec;24(6):701-8.

Hanaway P. Form Follows Function: A Functional Medicine Overview. The Permanente Journal. 2016 Fall; 20(4):16-109.

Kohut D. Integrative and Functional Nutrition Practices and use of the Integrative and Functional Medical Nutrition Therapy Radial Among Registered Dietitians. Doctoral Thesis, Syracuse University, 2014.

Kushner RF, Sorensen KW. Lifestyle medicine: the future of chronic disease management. Curr Opin Endocrinol Diabetes Obes. 2013 Oct;20(5):389-95.

Kussman M, Fay LB. Nutrigenomics and Personalized Nutrition: Science and Concept. Personalized Medicine. 2008;5(5):447-455

Pizzorno JE Jr. Clinical decision making-a functional medicine perspective. Glob Adv Health Med. 2012 Sep;1(4):8-13.

Behandlingsstudier

Abbott RD, Sherwin K, Klopf H et al. Efficacy of a Multimodal Online Lifestyle Intervention for Depressive Symptoms and Quality of Life in Individuals With a History of Major Depressive Disorder. Cureus. 2020 Jul 8;12(7):e9061.

Bisht B, Darling WG, White EC et al. Effects of a multimodal intervention on gait and balance of subjects with progressive multiple sclerosis: a prospective longitudinal pilot study. Degener Neurol Neuromuscul Dis. 2017:7 79–93.

Beidelschies M, Alejandro-Rodriguez M, Ji X et al. Association of the Functional Medicine Model of Care With Patient-Reported Health-Related Quality-of-Life Outcomes. JAMA Network Open. 2019;2(10):e1914017.

Bredesen DE, Amos EC, Canick J et al. Reversal of cognitive decline in Alzheimer’s disease. Aging. June 2016;8(6):1250-1258.

Cutshall SM, Bergstrom LR, Kalish DJ. Evaluation of a functional medicine approach to treating fatigue, stress, and digestive issues in women. Complement Ther Clin Pract. 2016 May;23:75-81.

Drisko J, Bischoff B, Hall M, McCallum R. Treating irritable bowel syndrome with a food elimination diet followed by food challenge and probiotics. J Am Coll Nutr. 2006 Dec;25(6):514-22.

Droz N, Hanaway P, Hyman M et al. The impact of functional medicine on patient-reported outcomes in inflammatory arthritis: A retrospective study. PLoS One. 2020 Oct 8;15(10):e0240416.

Franic D, Snapp C, DeBusk R. Newly developed functional medicine program in diabetes: impact on clinical and patient reported outcomes – functional medicine and quality of life. BMC Complement Altern Med. 2012; 12(Suppl 1): P250.

Gökyayla E, Ermertcan AT, Bilaç C. Functional medicine with dermatology insite: A systematic approach for diagnosis and treatment of chronic diseases. Dermatol Ther. 2020 May 31;e13729.

James R, Moore AL, Carpenter D, Miller T, Ledbetter C. Feasibility of a Functional Medicine Approach to Slowing Clinical Cognitive Decline in Patients Over Age 55: A Multiple Case Study Report. OBM Integrative and Complementary Medicine. 2019 Sept;4(3).

Ornish D, Magbanua MJM, Weidner G et al. Changes in prostate gene expression in men undergoing an intensive nutrition and lifestyle intervention. Proc Natl Acad Sci U S A. Jun 17, 2008; 105(24): 8369–8374.

Nutrition

Abbott RD, Sadowski A, Alt AG. Efficacy of the Autoimmune Protocol Diet as Part of a Multi-disciplinary, Supported Lifestyle Intervention for Hashimoto’s Thyroiditis. Cureus. 2019 Apr 27;11(4):e4556.

Ames BN. Prevention of mutation, cancer, and other age-associated diseases by optimizing micronutrient intake. J Nucleic Acids. 2010 Sep 22;2010.

Bush CL, Blumberg JB, El-Sohemy A et al. Toward the Definition of Personalized Nutrition: A Proposal by The American Nutrition Association. J Am Coll Nutr. 2020 Jan;39(1):5-15.

Calfio C, Gonzalez A, Singh SK et al. The Emerging Role of Nutraceuticals and Phytochemicals in the Prevention and Treatment of Alzheimer’s Disease. J Alzheimers Dis. 2020;77(1):33-51.

de Lorimier R, Shanahan C. Smart Prevention—Health Care Cost Savings Resulting from the Targeted Use of Dietary Supplements. Frost & Sullivan 2013.

Di Renzo L, Gualtieri P, Romano L et al. Role of Personalized Nutrition in Chronic-Degenerative Diseases. Nutrients. 2019 Jul 24;11(8):1707.

Fenech M et al. Nutrigenetics and Nutrigenomics: Viewpoints on the Current Status and Applications in Nutrition Research and Practice. J Nutrigenet Nutrigenomics. 2011 Jul; 4(2): 69–89.

Guoxiang X et al. Toward Personalized Nutrition: Comprehensive Phytoprofiling and Metabotyping. J Proteome Res. 2013 Apr 5;12(4):1547-59.

Hennig B et al. Nutrition can modulate the toxicity of environmental pollutants: implications in risk assessment and human health. Environ Health Perspect. 2012 Jun;120(6):771-4.

Houston M. The role of cellular micronutrient analysis, nutraceuticals, vitamins, antioxidants and minerals in the prevention and treatment of hypertension and cardiovascular disease. Ther Adv Cardiovasc Dis. 2010 Jun;4(3):165-83.

Houston M. The role of nutrition and nutraceutical supplements in the treatment of hypertension. World J Cardiol. 2014 Feb 26;6(2):38-66.

Lal A, Ames BN. Association of chromosome damage detected as micronuclei with hematological diseases and micronutrient status. Mutagenesis. 2011 Jan;26(1):57-62.

Zeevi D, Korem T, Zmora N et al. Personalized Nutrition by Prediction of Glycemic Responses. Cell. 2015 Nov 19;163(5):1079-1094.

Zmora N, Zeevi D, Korem T et al. Taking it Personally: Personalized Utilization
of the Human Microbiome in Health and Disease. Cell Host Microbe.
2016 Jan 13;19(1):12-20.

Epigenetik

Carlberg C. Nutrigenomics of Vitamin D. Nutrients. 2019 Mar 21;11(3):676.

Choi SW, Friso S. Epigenetics: A New Bridge between Nutrition and Health. Adv Nutr. 2010 Nov;1(1):8-16.

Divella R, Daniele A, Savino E, Paradiso A. Anticancer Effects of Nutraceuticals in the Mediterranean Diet: An Epigenetic Diet Model. Cancer Genomics Proteomics. 2020 Jul-Aug;17(4):335-350.

Entringer S, Buss C, Swanson JM, Cooper DM, Wing DA, Waffarn F, Wadhwa PD. Fetal programming of body composition, obesity, and metabolic function: the role of intrauterine stress and stress biology. J Nutr Metab. 2012:632548.

Fenech M1, El-Sohemy A, Cahill L, Ferguson LR, French TA, et al. Nutrigenetics and Nutrigenomics: Viewpoints on the Current Status and Applications in Nutrition Research and Practice. J Nutrigenet Nutrigenomics. 2011;4(2):69-89.

González-Becerra K, Ramos-Lopez O, Barrón-Cabrera E. Fatty acids, epigenetic mechanisms and chronic diseases: a systematic review. Lipids Health Dis. 2019 Oct 15;18(1):178.

Jirtle RL. The Agouti mouse: a biosensor for environmental epigenomics studies investigating the developmental origins of health and disease. Epigenomics. 2014;6(5):447-50.

Oberg E, Givant C, Fisk B et al. Epigenetics in Clinical Practice: Characterizing Patient and Provider Experiences with MTHFR Polymorphisms and Methylfolate. J Nutrigenet Nutrigenomics. 2015;8(3):137-50.

Owczarczyk-Saczonek A, Purzycka-Bohdan D, Nedoszytko B et al. Pathogenesis of psoriasis in the ”omic” era. Part III. Metabolic disorders, metabolomics, nutrigenomics in psoriasis. Dermatol Alergol. 2020 Aug;37(4):452-467.

Pavlidis C, Nebel JC, Katsila T, Patrinos GP. Nutrigenomics 2.0: The Need for Ongoing and Independent Evaluation and Synthesis of Commercial Nutrigenomics Tests’ Scientific Knowledge Base for Responsible Innovation. OMICS. 2016 Feb 1; 20(2): 65–68.

Ramos-Lopez O, Milagro FI, Allayee H et al. Guide for Current Nutrigenetic, Nutrigenomic, and Nutriepigenetic Approaches for Precision Nutrition Involving the Prevention and Management of Chronic Diseases Associated with Obesity. J Nutrigenet Nutrigenomics. 2017;10(1-2):43-62.

Shankar S, Kumar D, Srivastava RK. Epigenetic modifications by dietary phytochemicals: implications for personalized nutrition. Pharmacol Ther. 2013 Apr;138(1):1-17.

Supic G, Jagodic M, Magic Z. Epigenetics: a new link between nutrition and cancer. Nutr Cancer. 2013;65(6):781-92.